Assay Detail
Functional
CHEMBL3124368
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Antioxidant activity in human HepG2 cells assessed as inhibition of ABAP-induced intracellular peroxyl radical scavenging activity by measuring ROS production measured every 5 mins for 1 hr by absorbance assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Octulosonic acid derivatives from Roman chamomile (Chamaemelum nobile) with activities against inflammation and metabolic disorder.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.40 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 4.96 |
| CHEMBL3120612 | — | — | 1 | 4.58 |
| CHEMBL3120613 | — | — | 1 | 4.46 |
| CHEMBL3120615 | — | — | 1 | 4.22 |
| CHEMBL3120616 | — | — | 1 | 4.10 |
| CHEMBL3120614 | — | — | 1 | 4.07 |
| CHEMBL3120617 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL3120612 | — | IC50 | = | 26000.0 | nM | 4.58 |
| CHEMBL3120613 | — | IC50 | = | 34500.0 | nM | 4.46 |
| CHEMBL3120615 | — | IC50 | = | 59500.0 | nM | 4.22 |
| CHEMBL3120616 | — | IC50 | = | 79000.0 | nM | 4.10 |
| CHEMBL3120614 | — | IC50 | = | 86000.0 | nM | 4.07 |
| CHEMBL3120617 | — | IC50 | > | 100000.0 | nM | - |