Assay Detail
Functional
CHEMBL3128591
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Antiviral activity against Hepatitis C virus genotype 1b expressed in human Huh7.5.1 cells coexpressing NKR2AN after 3 days by luciferase reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potent Hepatitis C Virus NS5A Inhibitors Containing a Benzidine Core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.83 | 10.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3125176 | — | — | 1 | 10.55 |
| CHEMBL3125178 | — | — | 1 | 9.57 |
| CHEMBL3125177 | — | — | 1 | 9.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3125176 | — | EC50 | = | 0.028 | nM | 10.55 |
| CHEMBL3125178 | — | EC50 | = | 0.27 | nM | 9.57 |
| CHEMBL3125177 | — | EC50 | = | 0.43 | nM | 9.37 |