Assay Detail
Functional
CHEMBL3129139
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Antiviral activity against HCV genotype 1b infected in human HuH7 cells assessed as total cellular RNA after 5 days by RT-PCR analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Halting HCV Replication with NS5A Inhibitors and NS5B Polymerase Inhibitors: Effective New Treatments of HCV Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3125409 | — | — | 1 | 9.00 |
| CHEMBL2347318 | — | — | 1 | 7.00 |
| CHEMBL3125408 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3125409 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL2347318 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3125408 | — | EC50 | < | 1.0 | nM | - |