Assay Detail
Binding
CHEMBL3130561
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Escherichia coli J96 wild type FimH lectin domain expressed in Escherichia coli C43 (DE3) by reverse ITC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli J96 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Type 1 fimbrin D-mannose specific adhesin (CHEMBL4837) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
Publication
Study of the structural and dynamic effects in the FimH adhesin upon α-d-heptyl mannose binding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.72 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170455 | — | — | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170455 | — | Kd | = | 19.2 | nM | 7.72 |