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Assay Detail

CHEMBL3130639

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV1 integrase/LEDGF-75 (unknown origin) interaction
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibiting the HIV integration process: past, present, and the future.
Di Santo R.
J Med Chem (2014) 57 : 539 -566
PubMed 24025027 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.82 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1200748 CARBIDOPA 4.0 1 5.18
CHEMBL1487 ATORVASTATIN 4.0 1 5.05
CHEMBL3125907 1 4.60
CHEMBL813 EPROSARTAN 4.0 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1200748 CARBIDOPA IC50 = 6540.0 nM 5.18
CHEMBL1487 ATORVASTATIN IC50 = 8900.0 nM 5.05
CHEMBL3125907 IC50 = 25000.0 nM 4.60
CHEMBL813 EPROSARTAN IC50 = 36850.0 nM 4.43