Assay Detail
Binding
CHEMBL3131099
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of binding of wild type mBIMBH3 peptide to human Bcl-2 delta C22 mutant by surface plasmon resonance competition experiment
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.83 | 4.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL371861 | — | — | 1 | 4.83 |
| CHEMBL3125475 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL371861 | — | IC50 | = | 14700.0 | nM | 4.83 |
| CHEMBL3125475 | — | IC50 | > | 25000.0 | nM | - |