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Assay Detail

CHEMBL3131173

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HT-29 cells by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Sinugyrosanolide A, an unprecedented C-4 norcembranoid, from the Formosan soft coral Sinularia gyrosa.
Cheng SY, Shih NL, Chuang CT, Chiou SF, Yang CN, Wang SK, Duh CY.
Bioorg Med Chem Lett (2014) 24 : 1562 -1564
PubMed 24529868 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1237054 PLICAMYCIN 4.0 1 7.16
CHEMBL3127575 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1237054 PLICAMYCIN EC50 = 70.0 nM 7.16
CHEMBL3127575 EC50 > 20000.0 nM -