Assay Detail
Functional
CHEMBL3131471
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Antiviral activity against Influenza A virus J/8178/09 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Computer-guided approach to access the anti-influenza activity of licorice constituents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.47 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1229 | OSELTAMIVIR | 4.0 | 1 | 7.52 |
| CHEMBL600457 | GLABRONE | — | 1 | 4.46 |
| CHEMBL242341 | FORMONONETIN | 2.0 | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1229 | OSELTAMIVIR | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL600457 | GLABRONE | IC50 | = | 34700.0 | nM | 4.46 |
| CHEMBL242341 | FORMONONETIN | IC50 | = | 38200.0 | nM | 4.42 |