Assay Detail
Functional
CHEMBL3132033
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Antiviral activity against Hepatitis C virus infected in Huh-7 cells assessed as inhibition of HCV replicon by replicon assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.48 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223608 | — | — | 1 | 5.55 |
| CHEMBL223720 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223608 | — | EC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL223720 | — | EC50 | = | 4000.0 | nM | 5.40 |