Assay Detail
Binding
CHEMBL3132036
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Binding affinity to Hepatitis C virus IRES RNA subdomain 2a by mass spectrometry assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Internal ribosome entry site (IRES) (CHEMBL612412) ↗| Type | NUCLEIC-ACID |
| Organism | Hepacivirus hominis |
Publication
Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.40 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223720 | — | — | 1 | 6.14 |
| CHEMBL223608 | — | — | 1 | 6.07 |
| CHEMBL427101 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223720 | — | Kd | = | 720.0 | nM | 6.14 |
| CHEMBL223608 | — | Kd | = | 860.0 | nM | 6.07 |
| CHEMBL427101 | — | Kd | = | 100000.0 | nM | 4.00 |