Assay Detail
Binding
CHEMBL3134705
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of trypsin (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Metabolism-guided drug design
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.28 | 6.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL143024 | — | — | 1 | 6.67 |
| CHEMBL141889 | — | — | 1 | 6.60 |
| CHEMBL143418 | — | — | 1 | 6.10 |
| CHEMBL19080 | L-375378 | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL143024 | — | IC50 | = | 213.0 | nM | 6.67 |
| CHEMBL141889 | — | IC50 | = | 252.0 | nM | 6.60 |
| CHEMBL143418 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL19080 | L-375378 | IC50 | = | 1800.0 | nM | 5.75 |