Assay Detail
Binding
CHEMBL3135123
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Inhibition of aromatase (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Flavans from Desmos cochinchinensis as potent aromatase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.85 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117 | CHRYSIN | — | 1 | 6.10 |
| CHEMBL399910 | PINOCEMBRIN | 2.0 | 1 | 6.05 |
| CHEMBL3134108 | — | — | 1 | 5.75 |
| CHEMBL3134107 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117 | CHRYSIN | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL399910 | PINOCEMBRIN | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL3134108 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL3134107 | — | IC50 | = | 3300.0 | nM | 5.48 |