Assay Detail
Binding
CHEMBL3135194
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Inhibition of APT2 (unknown origin)
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.57 | 7.71 |
| Ki | 1 | 7.47 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3133031 | — | — | 1 | 7.71 |
| CHEMBL1673415 | PALMOSTATIN B | — | 2 | 7.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3133031 | — | IC50 | = | 19.6 | nM | 7.71 |
| CHEMBL1673415 | PALMOSTATIN B | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL1673415 | PALMOSTATIN B | IC50 | = | 37.7 | nM | 7.42 |