Assay Detail
Functional
CHEMBL3137666
Review assay metadata, readout intent, target linkage, and publication context from the same page.
OSM: Erythrocyte assay. NF54 with 3H-Hypoxanthine at 72hr time point.
118
Total Activities
118
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Open Source Malaria Deposition 2. http://malaria.ourexperiment.org
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 118 | 5.80 | 7.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3137625 | — | — | 1 | 7.78 |
| CHEMBL3137639 | — | — | 1 | 7.61 |
| CHEMBL3137637 | — | — | 1 | 7.47 |
| CHEMBL3137614 | — | — | 1 | 7.40 |
| CHEMBL3137623 | — | — | 1 | 7.36 |
| CHEMBL3137561 | — | — | 1 | 7.18 |
| CHEMBL3137556 | — | — | 1 | 7.00 |
| CHEMBL3137615 | — | — | 1 | 6.96 |
| CHEMBL3137616 | — | — | 1 | 6.96 |
| CHEMBL3137626 | — | — | 1 | 6.94 |
| CHEMBL3137553 | — | — | 1 | 6.91 |
| CHEMBL3137559 | — | — | 1 | 6.91 |
| CHEMBL3137636 | — | — | 1 | 6.85 |
| CHEMBL3137570 | — | — | 1 | 6.80 |
| CHEMBL3137565 | — | — | 1 | 6.76 |
| CHEMBL3137610 | — | — | 1 | 6.75 |
| CHEMBL3137631 | — | — | 1 | 6.72 |
| CHEMBL3137575 | — | — | 1 | 6.60 |
| CHEMBL3137635 | — | — | 1 | 6.58 |
| CHEMBL3137654 | — | — | 1 | 6.58 |
| CHEMBL3137602 | — | — | 1 | 6.55 |
| CHEMBL3137611 | — | — | 1 | 6.55 |
| CHEMBL3137645 | — | — | 1 | 6.55 |
| CHEMBL3137651 | — | — | 1 | 6.51 |
| CHEMBL3137619 | — | — | 1 | 6.50 |
| CHEMBL3137650 | — | — | 1 | 6.48 |
| CHEMBL3137608 | — | — | 1 | 6.44 |
| CHEMBL3137582 | — | — | 1 | 6.42 |
| CHEMBL3137629 | — | — | 1 | 6.42 |
| CHEMBL3137573 | — | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3137625 | — | EC50 | = | 16.68 | nM | 7.78 |
| CHEMBL3137639 | — | EC50 | = | 24.32 | nM | 7.61 |
| CHEMBL3137637 | — | EC50 | = | 33.82 | nM | 7.47 |
| CHEMBL3137614 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3137623 | — | EC50 | = | 44.08 | nM | 7.36 |
| CHEMBL3137561 | — | EC50 | = | 65.36 | nM | 7.18 |
| CHEMBL3137556 | — | EC50 | = | 101.2 | nM | 7.00 |
| CHEMBL3137616 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL3137615 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL3137626 | — | EC50 | = | 114.7 | nM | 6.94 |
| CHEMBL3137553 | — | EC50 | = | 124.0 | nM | 6.91 |
| CHEMBL3137559 | — | EC50 | = | 122.8 | nM | 6.91 |
| CHEMBL3137636 | — | EC50 | = | 140.4 | nM | 6.85 |
| CHEMBL3137570 | — | EC50 | = | 160.0 | nM | 6.80 |
| CHEMBL3137565 | — | EC50 | = | 173.4 | nM | 6.76 |
| CHEMBL3137610 | — | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL3137631 | — | EC50 | = | 191.1 | nM | 6.72 |
| CHEMBL3137575 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL3137654 | — | EC50 | = | 262.7 | nM | 6.58 |
| CHEMBL3137635 | — | EC50 | = | 262.1 | nM | 6.58 |
| CHEMBL3137645 | — | EC50 | = | 278.5 | nM | 6.55 |
| CHEMBL3137602 | — | EC50 | = | 280.0 | nM | 6.55 |
| CHEMBL3137611 | — | EC50 | = | 280.0 | nM | 6.55 |
| CHEMBL3137651 | — | EC50 | = | 309.0 | nM | 6.51 |
| CHEMBL3137619 | — | EC50 | = | 320.0 | nM | 6.50 |
| CHEMBL3137650 | — | EC50 | = | 332.1 | nM | 6.48 |
| CHEMBL3137608 | — | EC50 | = | 360.0 | nM | 6.44 |
| CHEMBL3137582 | — | EC50 | = | 380.0 | nM | 6.42 |
| CHEMBL3137629 | — | EC50 | = | 382.9 | nM | 6.42 |
| CHEMBL3137573 | — | EC50 | = | 430.0 | nM | 6.37 |
| CHEMBL3137630 | — | EC50 | = | 455.1 | nM | 6.34 |
| CHEMBL3137597 | — | EC50 | = | 470.0 | nM | 6.33 |
| CHEMBL3137624 | — | EC50 | = | 483.3 | nM | 6.32 |
| CHEMBL3137566 | — | EC50 | = | 509.6 | nM | 6.29 |
| CHEMBL3137638 | — | EC50 | = | 520.7 | nM | 6.28 |
| CHEMBL3137549 | — | EC50 | = | 546.8 | nM | 6.26 |
| CHEMBL3137562 | — | EC50 | = | 576.4 | nM | 6.24 |
| CHEMBL3137646 | — | EC50 | = | 569.7 | nM | 6.24 |
| CHEMBL3137644 | — | EC50 | = | 597.3 | nM | 6.22 |
| CHEMBL3137658 | — | EC50 | = | 609.5 | nM | 6.21 |
| CHEMBL3137641 | — | EC50 | = | 613.3 | nM | 6.21 |
| CHEMBL3137618 | — | EC50 | = | 650.0 | nM | 6.19 |
| CHEMBL3137555 | — | EC50 | = | 730.8 | nM | 6.14 |
| CHEMBL3137642 | — | EC50 | = | 738.0 | nM | 6.13 |
| CHEMBL3137564 | — | EC50 | = | 839.2 | nM | 6.08 |
| CHEMBL3137622 | — | EC50 | = | 830.0 | nM | 6.08 |
| CHEMBL3137584 | — | EC50 | = | 850.0 | nM | 6.07 |
| CHEMBL3137601 | — | EC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL3137659 | — | EC50 | = | 1121.0 | nM | 5.95 |
| CHEMBL3137581 | — | EC50 | = | 1340.0 | nM | 5.87 |