Assay Detail
Binding
CHEMBL3222547
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Binding affinity to human SST4 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Non-iminosugar glucocerebrosidase small molecule chaperones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.21 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103769 | — | — | 1 | 7.77 |
| CHEMBL1591268 | — | — | 1 | 7.72 |
| CHEMBL1355048 | — | — | 1 | 7.58 |
| CHEMBL1591395 | — | — | 1 | 6.80 |
| CHEMBL1590268 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103769 | — | Ki | = | 17.0 | nM | 7.77 |
| CHEMBL1591268 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL1355048 | — | Ki | = | 26.0 | nM | 7.58 |
| CHEMBL1591395 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL1590268 | — | Ki | = | 690.0 | nM | 6.16 |