Assay Detail
Binding
CHEMBL3222750
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Inhibition of Enterococcus faecalis recombinant type 1 methionine aminopeptidase expressed in Escherichia coli BL21 (DE3) using Met-pNA substrate
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Enterococcus faecalis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2-bipyridine based inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 1 | 5.18 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39879 | DIPYRIDYL | — | 1 | 5.18 |
| CHEMBL1374568 | — | — | 1 | - |
| CHEMBL1355 | SODIUM CITRATE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39879 | DIPYRIDYL | IC50 | = | 6670.0 | nM | 5.18 |
| CHEMBL1374568 | — | Inhibition | - | % | - | |
| CHEMBL1355 | SODIUM CITRATE | Inhibition | - | % | - |