Assay Detail
Binding
CHEMBL3223054
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Inhibition of Plasmodium falciparum recombinant falcipain 3
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of novel benzothiazole and triazole analogs as falcipain inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.85 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218778 | — | — | 1 | 5.30 |
| CHEMBL3218764 | — | — | 1 | 4.86 |
| CHEMBL3218765 | — | — | 1 | 4.83 |
| CHEMBL3218768 | — | — | 1 | 4.40 |
| CHEMBL3218779 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218778 | — | IC50 | = | 4950.0 | nM | 5.30 |
| CHEMBL3218764 | — | IC50 | = | 13770.0 | nM | 4.86 |
| CHEMBL3218765 | — | IC50 | = | 14940.0 | nM | 4.83 |
| CHEMBL3218768 | — | IC50 | = | 39740.0 | nM | 4.40 |
| CHEMBL3218779 | — | IC50 | > | 50000.0 | nM | - |