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Assay Detail

CHEMBL3223060

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of calf duodenum adenosine deaminase
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine deaminase (CHEMBL2966)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Minisci reactions: Versatile CH-functionalizations for medicinal chemists
Duncton MAJ
Medchemcomm (2011) 2 : 1135 -1161
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.27 6.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3218780 2 6.12
CHEMBL1399702 NEBULARINE 1 5.03
CHEMBL157495 1 5.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3218780 Ki = 760.0 nM 6.12
CHEMBL1399702 NEBULARINE Ki = 9300.0 nM 5.03
CHEMBL157495 Ki = 9400.0 nM 5.03
CHEMBL3218780 Ki = 12500.0 nM 4.90