Assay Detail
Binding
CHEMBL3223559
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to poly(A) tail mRNA (unknown origin) assessed as apparent binding constant by absorption spectroscopy
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Binding of 9-O-(-amino) alkyl ether analogues of the plant alkaloid berberine to poly(A): insights into self-structure induction
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.48 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | 4.0 | 1 | 6.39 |
| CHEMBL3217841 | — | — | 1 | 5.51 |
| CHEMBL3217842 | — | — | 1 | 5.39 |
| CHEMBL3217843 | — | — | 1 | 5.26 |
| CHEMBL3217844 | — | — | 1 | 5.19 |
| CHEMBL3217845 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | Ki | = | 410.0 | nM | 6.39 |
| CHEMBL3217841 | — | Ki | = | 3080.0 | nM | 5.51 |
| CHEMBL3217842 | — | Ki | = | 4050.0 | nM | 5.39 |
| CHEMBL3217843 | — | Ki | = | 5540.0 | nM | 5.26 |
| CHEMBL3217844 | — | Ki | = | 6460.0 | nM | 5.19 |
| CHEMBL3217845 | — | Ki | = | 7580.0 | nM | 5.12 |