Assay Detail
Binding
CHEMBL3223565
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Binding affinity to poly(A) tail mRNA (unknown origin) assessed as cooperative binding constant by dilution method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Binding of 9-O-(-amino) alkyl ether analogues of the plant alkaloid berberine to poly(A): insights into self-structure induction
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.49 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | 4.0 | 1 | 5.00 |
| CHEMBL3217841 | — | — | 1 | 4.53 |
| CHEMBL3217842 | — | — | 1 | 4.48 |
| CHEMBL3217843 | — | — | 1 | 4.39 |
| CHEMBL3217844 | — | — | 1 | 4.28 |
| CHEMBL3217845 | — | — | 1 | 4.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL3217841 | — | Ki | = | 29700.0 | nM | 4.53 |
| CHEMBL3217842 | — | Ki | = | 33000.0 | nM | 4.48 |
| CHEMBL3217843 | — | Ki | = | 41000.0 | nM | 4.39 |
| CHEMBL3217844 | — | Ki | = | 52000.0 | nM | 4.28 |
| CHEMBL3217845 | — | Ki | = | 58000.0 | nM | 4.24 |