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Assay Detail

CHEMBL3223779

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to His-tagged human recombinant truncated del4 VEGF165 (amino acid residues C137 to R165) expressed in Escherichia coli BL21 (DE3) cells by surface plasmon resonance assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type BL21-DE3
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vascular endothelial growth factor A, long form (CHEMBL1783)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Binding region and interaction properties of sulfoquinovosylacylglycerol (SQAG) with human vascular endothelial growth factor 165 revealed by biosensor-based assays
Takakusagi Y, Takakusagi K, Ida N, Takami M, Matsumoto Y, Kusayanagi T, Nakabayashi T, Aoki S, Murata H, Ohta K, Sugawara F, Sakaguchi K
Medchemcomm (2011) 2 : 1188 -1193
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3219622 1 5.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3219622 Kd = 1400.0 nM 5.85