Assay Detail
Binding
CHEMBL3223785
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum 3D7 cytochrome bc1 complex assessed as cytochrome c reduction by spectrophotometric analysis in presence of decylubiquinol
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum 3D7 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The development of quinoloneesters as novel antimalarial agents targeting the Plasmodium falciparum bc1protein complex
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.71 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3219636 | — | — | 1 | 8.89 |
| CHEMBL1450 | ATOVAQUONE | 4.0 | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3219636 | — | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL1450 | ATOVAQUONE | EC50 | = | 3.0 | nM | 8.52 |