Assay Detail

CHEMBL3224131

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity to FTase (unknown origin)

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Protein farnesyltransferase (CHEMBL2094108) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Protein farnesyltransferase (CHEMBL2094108) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Protein farnesyltransferase

CHEMBL2094108

Anchored from Assay target.

Protein identity Protein farnesyltransferase

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	7 — Homologous single protein target
Curated By	Autocuration

Target

Protein farnesyltransferase (CHEMBL2094108) ↗

Type	PROTEIN COMPLEX
Organism	Homo sapiens

Publication

Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.

Ochocki JD, Distefano MD.
Medchemcomm (2013) 4 : 476 -492
PubMed 25530833 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL69330	FARNESYL DIPHOSPHATE	—	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL69330	FARNESYL DIPHOSPHATE	Kd	=	2.0	nM	8.70