Assay Detail
Functional
CHEMBL3224328
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Antimalarial activity against chloroquine-sensitive Plasmodium falciparum
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial peroxides: advances in drug discovery and design
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 8.36 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3221639 | — | — | 1 | 8.41 |
| CHEMBL3221880 | — | — | 1 | 8.41 |
| CHEMBL3221879 | — | — | 1 | 8.41 |
| CHEMBL3221878 | — | — | 1 | 8.41 |
| CHEMBL3221877 | — | — | 1 | 8.41 |
| CHEMBL3221876 | — | — | 1 | 8.41 |
| CHEMBL3221875 | — | — | 1 | 8.41 |
| CHEMBL269513 | — | — | 1 | 8.40 |
| CHEMBL3221873 | — | — | 1 | 8.15 |
| CHEMBL3221874 | — | — | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3221639 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221880 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221879 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221878 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221877 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221876 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL3221875 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL269513 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL3221873 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL3221874 | — | IC50 | = | 7.0 | nM | 8.15 |