Assay Detail
Binding
CHEMBL3224822
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli beta-lactamase AmpC
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
An approach to enzyme inhibition employing reversible boronate ester formation
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.12 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34964 | — | — | 1 | 7.57 |
| CHEMBL143399 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34964 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL143399 | — | IC50 | = | 220.0 | nM | 6.66 |