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Assay Detail

CHEMBL3224961

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at dopamine D2 receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Are pyridazines privileged structures?
Wermuth CG
Medchemcomm (2011) 2 : 935 -941
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.27 8.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3221299 1 8.41
CHEMBL26 SULPIRIDE 3.0 1 8.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3221299 Ki = 3.9 nM 8.41
CHEMBL26 SULPIRIDE Ki = 7.6 nM 8.12