Assay Detail
Binding
CHEMBL3225091
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human uPA using Bzbeta-Ala-Gly-Arg-pNA as substrate
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Urokinase-type plasminogen activator (CHEMBL3286) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
New 3-amidinophenylalanine-derived inhibitors of matriptase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.08 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3219101 | — | — | 1 | 5.47 |
| CHEMBL3219100 | — | — | 1 | 5.36 |
| CHEMBL3219103 | — | — | 1 | 4.74 |
| CHEMBL3219102 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3219101 | — | Ki | = | 3400.0 | nM | 5.47 |
| CHEMBL3219100 | — | Ki | = | 4400.0 | nM | 5.36 |
| CHEMBL3219103 | — | Ki | = | 18100.0 | nM | 4.74 |
| CHEMBL3219102 | — | Ki | = | 18500.0 | nM | 4.73 |