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Assay Detail

CHEMBL3225166

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa lectin LecB after 1 hr by enzyme-linked lectin assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids
Johansson EMV, Kadam RU, Rispoli G, Crusz SA, Bartels K, Diggle SP, Camara M, Williams P, Jaeger K, Darbre T, Reymond J
Medchemcomm (2011) 2 : 418 -420
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.20 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3218456 1 6.85
CHEMBL3218457 1 6.82
CHEMBL3218458 1 6.18
CHEMBL6067643 L-FUCOSE 3.0 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3218456 IC50 = 140.0 nM 6.85
CHEMBL3218457 IC50 = 150.0 nM 6.82
CHEMBL3218458 IC50 = 660.0 nM 6.18
CHEMBL6067643 L-FUCOSE IC50 = 11000.0 nM 4.96