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Assay Detail

CHEMBL3225188

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A549 cells after 48 hrs by XTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Progress on lamellarins
Pla D, Albericio F, Alvarez M
Medchemcomm (2011) 2 : 689 -697
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 6.94 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3218975 1 7.40
CHEMBL3218976 1 7.40
CHEMBL301226 1 7.40
CHEMBL373114 LAMELLARIN D 1 7.22
CHEMBL3218977 1 6.52
CHEMBL3218978 1 6.52
CHEMBL3218733 1 6.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3218975 IC50 = 40.0 nM 7.40
CHEMBL3218976 IC50 = 40.0 nM 7.40
CHEMBL301226 IC50 = 40.0 nM 7.40
CHEMBL373114 LAMELLARIN D IC50 = 60.0 nM 7.22
CHEMBL3218977 IC50 = 300.0 nM 6.52
CHEMBL3218978 IC50 = 300.0 nM 6.52
CHEMBL3218733 IC50 = 740.0 nM 6.13