Assay Detail
Functional
CHEMBL3225193
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HepG2 cells after 48 hrs by XTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Progress on lamellarins
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.38 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218975 | — | — | 1 | 8.00 |
| CHEMBL373114 | LAMELLARIN D | — | 1 | 7.70 |
| CHEMBL3218976 | — | — | 1 | 7.70 |
| CHEMBL301226 | — | — | 1 | 7.70 |
| CHEMBL3218978 | — | — | 1 | 7.00 |
| CHEMBL3218733 | — | — | 1 | 6.89 |
| CHEMBL3218977 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218975 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL373114 | LAMELLARIN D | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3218976 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL301226 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3218978 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3218733 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL3218977 | — | IC50 | = | 200.0 | nM | 6.70 |