Assay Detail
Binding
CHEMBL3225243
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Binding affinity to human recombinant MAOB
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of multifunctional small molecule-based reversible monoamine oxidase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.08 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3219619 | — | — | 1 | 7.55 |
| CHEMBL3219618 | — | — | 1 | 7.40 |
| CHEMBL1984524 | — | — | 1 | 7.16 |
| CHEMBL887 | RASAGILINE | 4.0 | 1 | 6.16 |
| CHEMBL3219621 | — | — | 1 | 5.28 |
| CHEMBL3219620 | — | — | 1 | 5.02 |
| CHEMBL402456 | — | — | 1 | 4.01 |
| CHEMBL3219617 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3219619 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3219618 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL1984524 | — | Ki | = | 70.0 | nM | 7.16 |
| CHEMBL887 | RASAGILINE | Ki | = | 700.0 | nM | 6.16 |
| CHEMBL3219621 | — | Ki | = | 5300.0 | nM | 5.28 |
| CHEMBL3219620 | — | Ki | = | 9600.0 | nM | 5.02 |
| CHEMBL402456 | — | Ki | = | 97000.0 | nM | 4.01 |
| CHEMBL3219617 | — | Ki | = | 695000.0 | nM | - |