Assay Detail
Binding
CHEMBL3225447
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Binding affinity to biotinylated Escherichia coli 16S rRNA A-site
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Understanding and overcoming aminoglycoside resistance caused by N-6'-acetyltransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 6.12 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL364470 | — | — | 1 | 7.40 |
| CHEMBL3221602 | — | — | 1 | 6.10 |
| CHEMBL3221601 | — | — | 1 | 5.96 |
| CHEMBL427409 | NEAMINE | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL364470 | — | Kd | = | 40.0 | nM | 7.40 |
| CHEMBL3221602 | — | Kd | = | 800.0 | nM | 6.10 |
| CHEMBL3221601 | — | Kd | = | 1100.0 | nM | 5.96 |
| CHEMBL427409 | NEAMINE | Kd | = | 10000.0 | nM | 5.00 |