Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3227577

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human GST-tagged ROR gamma LBD (amino acids 250 to 518)/LxxLL motif containing SRC1 derived peptide (unknown origin) interaction by TR-FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nuclear receptor ROR-gamma (CHEMBL1741186)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthetic modulators of the retinoic acid receptor-related orphan receptors
Kamenecka TM, Lyda B, Chang MR, Griffin PR
Medchemcomm (2013) 4 : 764 -776
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.17 6.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL169 URSOLIC ACID 2.0 1 6.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL169 URSOLIC ACID IC50 = 680.0 nM 6.17