Assay Detail
Binding
CHEMBL3227742
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of guinea pig brain FAAH
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Amino-5-arylbenzoxazole derivatives as potent inhibitors of fatty acid amide hydrolase (FAAH)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.88 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184238 | URB-597 | 1.0 | 1 | 7.58 |
| CHEMBL560590 | — | — | 1 | 7.18 |
| CHEMBL3222191 | — | — | 1 | 6.37 |
| CHEMBL3217947 | — | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184238 | URB-597 | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL560590 | — | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL3222191 | — | IC50 | = | 423.0 | nM | 6.37 |
| CHEMBL3217947 | — | IC50 | = | 424.0 | nM | 6.37 |