Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3231506

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist at postsynaptic alpha-adrenergic receptor in rat vas deferens
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Vas deferens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Adrenergic receptor alpha (CHEMBL2094111)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Absolute configuration of glycerol derivatives. 7. Enantiomers of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-1,4-benzodioxane (WB-4101), a potent competitive alpha-adrenergic antagonist.
Nelson WL, Powell ML, Dyer DC.
J Med Chem (1979) 22 : 1125 -1127
PubMed 40029 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.80 9.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL25554 1 9.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL25554 Kd = 0.1585 nM 9.80