Assay Detail
Binding
CHEMBL3238574
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-DTG from sigma-2 opioid receptor in rat liver
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The σ2 receptor: a novel protein for the imaging and treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.88 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672032 | — | — | 1 | 8.22 |
| CHEMBL1672031 | — | — | 1 | 8.00 |
| CHEMBL583580 | — | — | 1 | 7.73 |
| CHEMBL573932 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672032 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL1672031 | — | Ki | = | 10.1 | nM | 8.00 |
| CHEMBL583580 | — | Ki | = | 18.8 | nM | 7.73 |
| CHEMBL573932 | — | Ki | = | 26.6 | nM | 7.58 |