Assay Detail
Binding
CHEMBL3238714
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Binding affinity to alpha7 nAChR (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL2492) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.20 | 10.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3235498 | — | — | 1 | 10.04 |
| CHEMBL3235495 | — | — | 1 | 9.62 |
| CHEMBL2380803 | — | — | 1 | 7.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3235498 | — | Ki | = | 0.092 | nM | 10.04 |
| CHEMBL3235495 | — | Ki | = | 0.24 | nM | 9.62 |
| CHEMBL2380803 | — | Ki | = | 11.6 | nM | 7.94 |