Assay Detail
Binding
CHEMBL3239093
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Inhibition of human ACAT2
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.44 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3233888 | — | — | 1 | 5.96 |
| CHEMBL3233890 | — | — | 1 | 5.81 |
| CHEMBL3233872 | — | — | 1 | 5.52 |
| CHEMBL3233884 | — | — | 1 | 5.01 |
| CHEMBL3233891 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3233888 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL3233890 | — | IC50 | = | 1555.0 | nM | 5.81 |
| CHEMBL3233872 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3233884 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL3233891 | — | IC50 | = | 13300.0 | nM | 4.88 |