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Assay Detail

CHEMBL3239270

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 96 hrs by crystal violet staining
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis, pharmacological evaluation, and σ1 receptor interaction analysis of hydroxyethyl substituted piperazines.
Weber F, Brune S, Korpis K, Bednarski PJ, Laurini E, Dal Col V, Pricl S, Schepmann D, Wünsch B.
J Med Chem (2014) 57 : 2884 -2894
PubMed 24617836 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3233532 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3233532 IC50 = 15000.0 nM 4.82