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Assay Detail

CHEMBL3239407

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]DPDPE from delta opioid receptor in guinea pig brain membranes after 1 hr
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Brain
Subcellular Membrane
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity.
Cai J, Song B, Cai Y, Ma Y, Lam AL, Magiera J, Sekar S, Wyse BD, Ambo A, Sasaki Y, Lazarus LH, Smith MT, Li T.
Bioorg Med Chem (2014) 22 : 2208 -2219
PubMed 24613457 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL340032 DADLE 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL340032 DADLE Ki = 0.3 nM 9.52