Assay Detail
Functional
CHEMBL3240060
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Antimalarial activity against Plasmodium falciparum assessed as growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The chemistry and biology of febrifugine and halofuginone.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 7.45 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479432 | FEBRIFUGINE | — | 1 | 9.15 |
| CHEMBL314435 | — | — | 1 | 8.43 |
| CHEMBL314682 | — | — | 1 | 8.07 |
| CHEMBL3238413 | — | — | 1 | 7.70 |
| CHEMBL3238411 | — | — | 1 | 6.04 |
| CHEMBL3238412 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479432 | FEBRIFUGINE | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL314435 | — | EC50 | = | 3.7 | nM | 8.43 |
| CHEMBL314682 | — | EC50 | = | 8.6 | nM | 8.07 |
| CHEMBL3238413 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3238411 | — | EC50 | = | 910.0 | nM | 6.04 |
| CHEMBL3238412 | — | EC50 | = | 4800.0 | nM | 5.32 |