Assay Detail
Functional
CHEMBL3240176
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Growth inhibition of HUVEC by WST-8 assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potential anti-angiogenesis effects of p-terphenyl compounds from Polyozellus multiplex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.22 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178455 | — | — | 1 | 5.85 |
| CHEMBL3236668 | — | — | 1 | 5.47 |
| CHEMBL3236669 | — | — | 1 | 5.12 |
| CHEMBL458248 | POLYOZELLIN | — | 1 | 4.99 |
| CHEMBL3236670 | — | — | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178455 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3236668 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL3236669 | — | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL458248 | POLYOZELLIN | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL3236670 | — | IC50 | = | 21400.0 | nM | 4.67 |