Assay Detail
Binding
CHEMBL3240177
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human VEGFR2
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potential anti-angiogenesis effects of p-terphenyl compounds from Polyozellus multiplex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.55 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178455 | — | — | 1 | 5.62 |
| CHEMBL3236669 | — | — | 1 | 4.50 |
| CHEMBL3236670 | — | — | 1 | 4.28 |
| CHEMBL458248 | POLYOZELLIN | — | 1 | 4.18 |
| CHEMBL3236668 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178455 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL3236669 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL3236670 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL458248 | POLYOZELLIN | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL3236668 | — | IC50 | = | 70000.0 | nM | 4.16 |