Assay Detail
Binding
CHEMBL3240239
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Bacillus cereus metallo-beta-lactamase BcII
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus cereus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-β-lactamases and arginases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.55 | 7.05 |
| IC50 | 1 | 5.04 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3234727 | — | — | 1 | 7.05 |
| CHEMBL3234728 | — | — | 1 | 7.05 |
| CHEMBL3234729 | — | — | 1 | 7.05 |
| CHEMBL119888 | THIOSALICYLIC ACID | — | 1 | 5.04 |
| CHEMBL1224557 | BENZENEMETHANETHIOL | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3234727 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL3234728 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL3234729 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL119888 | THIOSALICYLIC ACID | Ki | = | 9200.0 | nM | 5.04 |
| CHEMBL1224557 | BENZENEMETHANETHIOL | IC50 | = | 9200.0 | nM | 5.04 |