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Assay Detail

CHEMBL3240242

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse macrophage arginase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-β-lactamases and arginases.
McGeary RP, Schenk G, Guddat LW.
Eur J Med Chem (2014) 76 : 132 -144
PubMed 24583353 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1234777 NOR-NOHA 1.0 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1234777 NOR-NOHA IC50 = 50000.0 nM 4.30