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Assay Detail

CHEMBL3243540

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HeLa cells after 24 hrs by XTT assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Fluorescent analog of OSW-1 and its cellular localization.
Yamada R, Takeshita T, Hiraizumi M, Shinohe D, Ohta Y, Sakurai K.
Bioorg Med Chem Lett (2014) 24 : 1839 -1842
PubMed 24613377 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.45 8.59
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL375269 1 8.59
CHEMBL3233176 1 8.30
CHEMBL3233177 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL375269 IC50 = 2.6 nM 8.59
CHEMBL3233176 IC50 = 5.0 nM 8.30
CHEMBL3233177 Inhibition - % -