Assay Detail
Functional
CHEMBL3253383
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of radiolabeled 5-hydroxytryptamine uptake in whole rat brain synaptosome
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Substituted 3-amino-1,1-diaryl-2-propanols as potential antidepressant agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.01 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3250734 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3250734 | — | IC50 | = | 9800.0 | nM | 5.01 |