Assay Detail
Binding
CHEMBL3259189
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive reversible inhibition of porcine pancreatic kallikrein using N-benzoyl-L-prolyl-L-phenylalanyl-L-arginine p-nitroanilide hydrochloride as substrate after 15 to 180 mins by Michaelis-Menten plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.14 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL352923 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL352923 | — | Ki | = | 730.0 | nM | 6.14 |