Assay Detail
Binding
CHEMBL3266102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DDR2 (unknown origin) after 120 mins by radiometric assay in presence of gamma-[33P]-ATP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Discoidin domain-containing receptor 2 (CHEMBL5122) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of type II and III DDR2 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.35 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2403816 | — | — | 1 | 7.75 |
| CHEMBL1738943 | — | — | 1 | 7.19 |
| CHEMBL2403875 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2403816 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL1738943 | — | IC50 | = | 65.0 | nM | 7.19 |
| CHEMBL2403875 | — | IC50 | = | 75.0 | nM | 7.12 |