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Assay Detail

CHEMBL3266366

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of telomerase (unknown origin) incubated for 60 mins at 30 degC followed by 5 mins at 95 degC by TRAP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Interactions of cyclic and non-cyclic naphthalene diimide derivatives with different nucleic acids.
Czerwinska I, Sato S, Juskowiak B, Takenaka S.
Bioorg Med Chem (2014) 22 : 2593 -2601
PubMed 24726302 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.84 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3262313 1 6.46
CHEMBL287201 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3262313 EC50 = 350.0 nM 6.46
CHEMBL287201 EC50 = 6000.0 nM 5.22